Consistency: Strong. Deep research (Falcon → HNRNPU substrate, HIV-1 latency reversal; mouse meiotic CCNB1/MPF role), UniProt and GOA agree on SCF substrate-receptor role. Review core MF = GO:1990756. No contradictions. PMID:36285453 (HNRNPU/HIV) verified, is the UniProt FUNCTION source.
PN story / NEW pressure: PN asserts only the generic adaptor MF. Like FBXO33, FBXO34's GOA has NO ubiquitin-ligase/transferase MF to MODIFY — only protein binding IPI (mostly sticky Y2H KRTAPs), SCF complex CC and SCF catabolism BP (both NAS/ComplexPortal). So GO:1990756 is inferred-only here too, justified by the HNRNPU degradation evidence. Substrate repertoire thin (one human substrate); review correctly proposes no substrate-specific NEW terms (proposed_new_terms empty). Conclusion: PN adaptor claim = defensible ADD to GOA (GO:1990756 verified real); flag adaptor MF as inferred-only with a single validated substrate.
Mapping strategy: Correct; gene does not change the node. GO:1990756 equals the review's core MF and genuinely adds value (no MF in GOA). The large block of high-throughput protein-binding IPIs (KRTAPs, MTUS2, KRT40) are correctly kept non-core / flagged as likely non-physiological.
Evidence alignment: PN cites only "15340381 / rev". Review anchored on PMID:36285453 (HNRNPU/HIV, verified) + Falcon (Yang 2022 human; Zhao 2021/Kinterova 2022 mouse meiosis, orthology-based UNVERIFIED) + interactome PMIDs + PMID:34445249. PN reference disjoint from review's.
Verdict: CONSISTENT — no edits required; flag GO:1990756 core MF as inferred-only (one validated substrate, HNRNPU).