PN placement:ALP → Autophagosome closure maturation and lysosome fusion → Sealing of autophagophore membrane → ESCRT-III complex component AND ALP → Microautophagy → General microautophagy machinery → ESCRT-III complex component (2 rows; shared CHMP template)
PN-node mapping: type → GO:0000815 ESCRT III complex (already_in_goa_exact); "Sealing" group → GO:0000045 autophagosome assembly (more_specific_than_existing_goa); classes context_only/too_broad; branch no_mapping.
Consistency: Mostly consistent, with a real specificity tension. The review identifies CHMP7 as an ESCRT-II/ESCRT-III hybrid whose most specific role is nuclear-envelope hole sealing via LEMD2 binding and CHMP4B recruitment — not autophagosome closure. PN lumps CHMP7 into the generic ESCRT-III sealing/microautophagy component buckets. The review's autophagy entries (GO:0097352 IEA, KEEP_AS_NON_CORE) are flagged as "plausible secondary ESCRT pathway / broad location context." The PN-vs-review divergence is in emphasis (NE sealing vs autophagosome sealing), not factual contradiction.
PN story / NEW pressure: PN projects GO:0000045 autophagosome assembly (verified real); for CHMP7 the support is family/membership-level, so a gene-specific assertion would over-reach. Notably the review's own NEW pressure is elsewhere — a suggested_question asks for a more specific GO term for ESCRT-mediated nuclear-envelope hole sealing during anaphase (proposed_new_terms is empty; that is a candidate, unverified gap). PN over-reaches on autophagy for CHMP7 — already captured non-core; do not ADD GO:0000045.
Mapping strategy: No change to the ALP node. CHMP7's distinctive function is nuclear-envelope/ESCRT-II-III hybrid, peripheral to the autophagosome-sealing node; GO:0000815 leaf is defensible, the "Sealing" group→GO:0000045 projection is a weak gene-specific fit (class context_only is the correct ceiling).
Evidence alignment: Divergent. PN cites only the Cells "Key Regulators of Autophagosome Closure" review. Review cites primary ESCRT/NE-sealing literature (incl. PMID:36107470 ESCRT-III-MIT interactome [verified, not the PN review]). No shared specific citations.
Verdict: Consistent; review correctly centers NE sealing and treats PN's autophagy placement as non-core. Recommended edits: none for autophagy; (optional, out-of-scope) the NE-hole-sealing GO gap the review flags is worth pursuing separately.