Reactome MF Verdict Slice
Back to Reactome-GO Alignment
Generated by inventory_reactome.py from the molecular-function subset of data/gene_reactome_annotations.tsv.
Rows without a manual verdict are candidate triage rows derived from the current gene-review action: ACCEPT and KEEP_AS_NON_CORE seed reaction_mf_exact, but they have not all been independently checked against the Reactome event graph.
Candidate Verdicts
| Candidate verdict |
Rows |
| reaction_mf_exact |
781 |
| reaction_mf_refine |
99 |
| insufficient_event_detail |
7 |
| activity_contradicted |
5 |
| contested_direct_activity |
3 |
| regulator_not_executor |
3 |
| wrong_executor |
2 |
| wrong_go_branch |
2 |
| nonphysiological_side_activity |
1 |
| obsolete_go_term |
1 |
| wrong_transport_mechanism |
1 |
Review-Action Buckets
| Bucket |
Rows |
| accepted_mf |
745 |
| mf_term_refinement |
80 |
| accepted_non_core_mf |
36 |
| broad_parent_or_duplicate |
19 |
| undecided_mf |
7 |
| activity_contradicted |
5 |
| contested_direct_activity |
3 |
| regulator_not_executor |
3 |
| wrong_executor |
2 |
| wrong_go_branch |
2 |
| nonphysiological_side_activity |
1 |
| obsolete_go_term |
1 |
| wrong_transport_mechanism |
1 |
Manual Failure Modes
| Failure mode |
Rows |
| broad_parent_or_duplicate |
19 |
| activity_contradicted |
5 |
| contested_direct_activity |
3 |
| regulator_not_executor |
3 |
| wrong_executor |
2 |
| wrong_go_branch |
2 |
| nonphysiological_side_activity |
1 |
| obsolete_go_term |
1 |
| wrong_transport_mechanism |
1 |
Existing Review Actions
| Review action |
Rows |
| ACCEPT |
745 |
| MODIFY |
80 |
| KEEP_AS_NON_CORE |
36 |
| MARK_AS_OVER_ANNOTATED |
25 |
| REMOVE |
12 |
| UNDECIDED |
7 |
Repeated Reactome Events
| Reactome ID |
Rows |
Genes |
Actions |
Event |
| R-HSA-8981637 |
5 |
5 |
ACCEPT:4, REMOVE:1 |
RHOA GAPs stimulate RHOA GTPase activity |
| R-HSA-1482533 |
4 |
4 |
ACCEPT:1, KEEP_AS_NON_CORE:1, MODIFY:1, UNDECIDED:1 |
2-acyl LPC is acylated to PC by LPCAT |
| R-HSA-1482547 |
4 |
4 |
ACCEPT:2, MODIFY:1, UNDECIDED:1 |
1-acyl LPC is acylated to PC by LPCAT |
| R-HSA-8867288 |
4 |
4 |
ACCEPT:4 |
OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 |
| R-HSA-1454916 |
3 |
3 |
ACCEPT:1, MODIFY:1, REMOVE:1 |
The ABCC family mediates organic anion transport |
| R-HSA-1482539 |
3 |
3 |
MODIFY:2, ACCEPT:1 |
1-acyl LPG is acylated to PG by LPGAT |
| R-HSA-1482635 |
3 |
3 |
ACCEPT:1, REMOVE:1, MODIFY:1 |
2-acyl LPG is acylated to PG by LPGAT |
| R-HSA-2404131 |
3 |
3 |
ACCEPT:1, KEEP_AS_NON_CORE:1, MODIFY:1 |
LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol |
| R-HSA-3165230 |
3 |
3 |
ACCEPT:3 |
SLC52A1,2,3 transport RIB from extracellular region to cytosol |
| R-HSA-3371422 |
3 |
3 |
ACCEPT:3 |
ATP hydrolysis by HSP70 |
Repair-Prone GO Terms
| GO term in MODIFY/MARK_AS_OVER_ANNOTATED rows |
Rows |
| GO:0008106 alcohol dehydrogenase (NADP+) activity |
6 |
| GO:0004674 protein serine/threonine kinase activity |
5 |
| GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity |
5 |
| GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity |
4 |
| GO:0000026 alpha-1,2-mannosyltransferase activity |
4 |
| GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity |
4 |
| GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity |
4 |
| GO:0008395 steroid hydroxylase activity |
3 |
| GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups |
3 |
| GO:0016416 O-palmitoyltransferase activity |
3 |
Output Table